Cover of “Medical Microbiology, Virology, Immunology : textbook. Vol. 1”

Medical Microbiology, Virology, Immunology : textbook. Vol. 1

учебник

Zverev V.V., Boichenko M.N.

  • ГЭОТАР-Медиа
  • 2020
  • 384 pages

Medical subjects

$22$16−27%
Read
This publication has been prepared by staff members of Microbiology, Virology and Immunology Departments of I.M. Sechenov First Moscow State Medical University, Pirogov Russian National Research Medical University, A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Pavlov First Saint Petersburg State Medical University, S.M. Kirov Military Medical Academy, State Medical Universities of Omsk, Orenburg, Chelyabinsk.

The textbook is comprised of two volumes, which include 19 chapters, sequentially introducing the issues of general and special microbiology, virology, and immunology. The material presented in both volumes is significantly revised according to the modern science trends and supplemented by illustrations, tables and figures. The textbook is composed in compliance with the approved off icial educational program, and is recommended for the students of the departments of General Medicine, Pediatrics and Preventice Medicine.

  1. 01COMPOSITE AUTHORS
  2. 02LIST OF ABBREVIATIONS
  3. 03Part I. GENERAL MICROBIOLOGY
    1. Chapter 1. Introduction to microbiology and immunology (V.N. Tsarev)
      1. 1.1. The subject of medical microbiology
      2. 1.2. Objectives and methods of medical microbiology
      3. 1.3. Discovery of microbes and study of the microbial world
      4. Revision tasks (for self-control)
    2. Chapter 2. Microbial morphology and classification
      1. 2.1. Microbial systematics and nomenclature (E.P. Pashkov, L.I. Petrova)
      2. 2.2. Bacterial classification and morphology
        1. 2.2.1. Morphological forms of bacteria
        2. 2.2.2. Bacterial cell structure
        3. 2.2.3. Structural features of spirochetes, rickettsia, chlamydia, actinomyces and mycoplasma
      3. 2.3. Structure and classification of fungi (A.S. Bykov)
      4. 2.4. Structure and classification of protozoa (A.S. Bykov)
      5. 2.5. Structure and classification of viruses (A.S. Bykov)
      6. Revision tasks (for self-control)
    3. Chapter 3. Microbial physiology
      1. 3.1. Bacterial physiology (M.N. Boichenko, V.V. Tets)
        1. 3.1.1. Nutrition in bacteria
        2. 3.1.2. Bacterial enzymes
        3. 3.1.3. Energy metabolism
        4. 3.1.4. Structural metabolism
        5. 3.1.5. Substance transfer
        6. 3.1.6. Regulation of bacterial metabolism
        7. 3.1.7. Morphogenesis of bacteria and bacterial communities
        8. 3.1.8. Secondary metabolism
        9. 3.1.9. Attitude to environmental factors
        10. 3.1.10. Growth and reproduction
        11. 3.1.11. Conditions for bacterial culturing
        12. 3.1.12. Bacterial behavior in bacterial communities
      2. 3.2. Viral physiology (V.V. Zverev, A.S. Bykov)
        1. 3.2.1. Productive virus-cell interaction
        2. 3.2.2. Programmed cell death (apoptosis)
        3. 3.2.3. Nonproductive infections
      3. 3.3. Viral cultivation
      4. 3.4. Bacteriophages (bacterial viruses)
      5. Revision tasks (for self-control)
    4. Chapter 4. Microbial ecology - microecology
      1. 4.1. The spread of microbes (A.S. Bykov, E.P. Pashkov)
        1. 4.1.1. Role of microorganisms in the cycle of matter in nature
        2. 4.1.2. Soil microflora
        3. 4.1.3. Water microflora
        4. 4.1.4. Air microflora
        5. 4.1.5. Microflora of household and medical facilities
      2. 4.2. Human microflora (L.I. Kafarskaya, A.S. Bykov)
      3. 4.3. Elimination of microbes in the environment (V.B. Sboychakov)
        1. 4.3.1. Disinfection
        2. 4.3.2. Sterilization
        3. 4.3.3. Asepsis and antisepsis
      4. 4.4. Sanitary microbiology (V.B. Sboychakov)
        1. 4.4.1. Sanitary-microbiological study of water
        2. 4.4.2. Sanitary-microbiological study of soil
        3. 4.4.3. Assessment of microbial content of aerial environment
        4. 4.4.4. Sanitary-microbiological control in food supply facilities
      5. Revision tasks (for self-control)
    5. Chapter 5. Microbial genetics (M.N. Boichenko)
      1. 5.1. Bacterial genome structure
        1. 5.1.1. Bacterial chromosome
        2. 5.1.2. Bacterial plasmids
        3. 5.1.3. Mobile genetic elements
        4. 5.1.4. Integrons
        5. 5.1.5. Pathogenicity islands (PAIs)
        6. 5.1.6. Systems for regulating gene expression. Protection against foreign deoxyribonucleic acid
      2. 5.2. Mutations in bacteria
      3. 5.3. Recombination in bacteria
        1. 5.3.1. Homologous recombination
        2. 5.3.2. Site-specific recombination
        3. 5.3.3. Illegitimate or replicative recombination
      4. 5.4. Transfer of genetic information in bacteria
        1. 5.4.1. Conjugation
        2. 5.4.2. Transduction
        3. 5.4.3. Transformation
      5. 5.5. Specific aspects of viral genetics
      6. 5.6. Use of genetic methods in the diagnosis of infectious diseases
        1. 5.6.1. Methods for the intraspecific identification of bacteria
        2. 5.6.2. Methods for microbial identification without isolation in pure culture
        3. 5.6.2. The basics of genetic engineering
      7. Revision tasks (for self-control)
    6. Chapter 6. Antimicrobial chemotherapeutic agents
      1. 6.1. Antimicrobial chemotherapeutic agents (L.I. Kafarskaya, N.V. Davydova, N.V. Horoshko)
        1. 6.1.1. Antibiotics
        2. 6.1.2. Synthetic antimicrobial chemotherapeutic agents
      2. 6.2. Mechanisms of action of antimicrobial chemotherapeutic agents effective against cellular forms of microorganisms
        1. 6.2.1. Inhibitors of synthesis and functions of bacterial cell wall
        2. 6.2.2. Inhibitors of bacterial protein synthesis
        3. 6.2.3. Inhibitors of nucleic acid synthesis
        4. 6.2.4. Inhibitors of cytoplasmic membrane functions
        5. 6.2.5. Collateral effects on microorganisms
      3. 6.3. Medicinal resistance of bacteria
        1. 6.3.1. Natural resistance
        2. 6.3.2. Acquired resistance
        3. 6.3.3. The genetic basis for acquired resistance
        4. 6.3.4. Implementation of the acquired resistance
      4. 6.4. Assessment of bacterial sensitivity to antibiotics
      5. 6.5. Complications of antimicrobial chemotherapy in the macroorganism
      6. Revision tasks (for self-control)
    7. Chapter 7. The infection study (O.V. Bukharin)
      1. 7.1. Infection. Forms of infectious process
      2. 7.2. Driving forces for infectious process
      3. 7.3. Role of a pathogen in the infectious process and its main biological characteristics
        1. 7.3.1. Virulence factors
        2. 7.3.2. Pathogenic factors of infectious agents
        3. 7.3.3. Genetics of bacterial virulence
      4. 7.4. Role of a microorganism in the infectious process
        1. 7.4.1. Anatomical and physiological barriers in infection
      5. 7.5. Role of the environment in the infectious process
      6. Revision tasks (for self-control)
  4. 04Part II. GENERAL IMMUNOLOGY
    1. Chapter 8. The study of immunity and factors of innate immunity (I.I. Dolgushin, O.A. Svitich)
      1. 8.1. Introduction to immunology
        1. 8.1.1. Milestones of the development of immunology
        2. 8.1.2. Types of immunity
      2. 8.2. Innate immunity
        1. 8.2.1. Factors of innate immunity
        2. 8.2.2. Humoral factors of innate immunity
        3. 8.2.3. Receptors of innate immunity
        4. 8.2.4. Cells of innate immunity
      3. Revision tasks (for self-control)
    2. Chapter 9. Antigens and the human immune system (Yu.V. Nesvizhskiy)
      1. 9.1. Antigens
        1. 9.1.1. General information
        2. 9.1.2. Properties of antigens
        3. 9.1.3. Classification of antigens
        4. 9.1.4. Human antigens
        5. 9.1.5. Microbial antigens
        6. 9.1.6. Antigenic processes in macroorganism
      2. 9.2. Human immune system
        1. 9.2.1. Structurally functional elements of the immune system
        2. 9.2.2. Functional organization of the immune system
      3. Revision tasks (for self-control)
    3. Chapter 10. Main types of the immune response (yu.v. Nesvizhskiy)
      1. 10.1. Antibodies and antibody formation
        1. 10.1.1. Nature of antibodies
        2. 10.1.2. Molecular structure of antibodies
        3. 10.1.3. Structural and functional features of different classes of immunoglobulins
        4. 10.1.4. Antigenicity of antibodies
        5. 10.1.5. Mechanism of antibody/antigen interaction
        6. 10.1.6. Properties of antibodies
        7. 10.1.7. Genetics of immunoglobulins
        8. 10.1.8. Dynamics of antibody production
        9. 10.1.9. The study of antibody diversity
      2. 10.2. Immune phagocytosis
      3. 10.3. Cell-mediated killing
        1. 10.3.1. Antibody-dependent cell-mediated cytotoxicity
        2. 10.3.2. Antibody-independent cell-mediated cytotoxicity
      4. 10.4. Hypersensitivity reaction
      5. 10.5. Immunological memory
      6. 10.6. Immunological tolerance
      7. Revision tasks (for self-control)
    4. Chapter 11. The specificity of the immune reactions in various locations and conditions (Yu.V. Nesvizhskiy)
      1. 11.1. The specificity of local immunity
        1. 11.1.1. Skin immunity
        2. 11.1.2. Mucosal immunity
      2. 11.2. The specificity of the immune response in various conditions
        1. 11.2.1. The specificity of the immune response to bacterial infections
        2. 11.2.2. The specificity of antiviral immunity
        3. 11.2.3. The specificity of antifungal immunity
        4. 11.2.4. The specificity of the immune response to protozoal invasion
        5. 11.2.5. The specificity of antihelminthic immunity
        6. 11.2.6. Transplantation immune response
        7. 11.2.7. Immune responses to tumors
        8. 11.2.8. Immunology of pregnancy
      3. 11.3. Immune status and its evaluation
      4. 11.4. Pathology of the immune system
        1. 11.4.1. Immunodeficiency disorders
        2. 11.4.2. Autoimmune diseases
        3. 11.4.3. Allergic diseases
        4. 11.4.4. Lymphoproliferative disorders
      5. 11.5. Immunocorrection
      6. Revision tasks (for self-control)
    5. Chapter 12. Immune reactions (Yu.V. Nesvizhskiy)
      1. 12.1. Antigen-antibody reactions and their application
      2. 12.2. Agglutination assay
      3. 12.3. Precipitation assay
      4. 12.4. Complement tests
      5. 12.5. Labeled antibody or antigen test
      6. 12.6. Neutralization test
    6. Chapter 13. Immunoprophylaxis and immune therapy (V.V. Zverev, L.I. Petrova)
      1. 13.1. Essence and place of immunoprophylaxis and immune therapy in medical practice
      2. 13.2. Immunobiological drugs
        1. 13.2.1. General characteristics and classification of immunobiological drugs
        2. 13.2.2. Vaccines
        3. 13.2.3. Bacteriophages
        4. 13.2.4. Probiotics
        5. 13.2.5. Immunobiological drugs based on specific antibodiesи
      3. Revision tasks (for self-control) (to chapters 12, 13)
  5. 05KEYS TO THE TESTS

$22$16−27%